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ABOUT SIBUTRAMINE 10MG CAPSULES ( OBESTAT )
Obestat capsules are made in India by respected pharmaceutical giant Cipla. Obestat capsules contain 10mg Sibutramine Hydrochloride. Sibutramine Hydrochloride is sold throughout Europe under the brand name Reductil and in the U.S under the brand name Meridia. Obestat, Reductil and Meridia all contain exactly the same chemical - Sibutramine Hydrochloride, however, Obestat costs significantly less than the other 2 products as Indian companies are able to produce and therefore sell at a fraction of the prices charged in the U.S and Europe.

WHAT IS SIBUTRAMINE USED FOR?

Sibutramine is a medicine to help with weight loss with people who are obese or overweight.

HOW DOES SIBUTRAMINE WORK?

Sibutramine works by reducing appetite and enhancing feeling of 'fullness' . On this basis, sibutramine can be described as a weight loss 'aid' rather than a 'wonder-drug' as less food needs to be consumed in order to lose weight.

HOW EFFECTIVE IS SIBUTRAMINE AS A WEIGHT LOSS AID?

If used as part of an overall weight loss programme, Sibutramine can be very effective. Recent studies have shown that Sibutramine plus a weight-reducing diet and an exercise programme causes more weight loss than a weight reducing diet and exercise alone. A body weight loss of 7% or greater is not unusual within a 6-12 month period with the help of Sibutramine.

The main reason that some people may experience unsatisfactory results using Sibutramine is that a weight reducing diet is not adhered to. As previously stated, Sibutramine works by suppressing the appetite. A weight-reducing diet and ideally, an exercise programme is necessary for obtaining maximum results.

THE MEDICAL GUIDELINES FOR THE USE OF SIBUTRAMINE ARE AS FOLLOWS:
* Sibutramine use is advised for people who have experienced difficulty losing weight over a 3 month period using a weight reducing diet and exercise alone.

* BMI ( Body Mass Index ) must be 30 or above or 27 or above where a medical condition exists ( for example, diabetes ) that would benefit from weight loss.

* There should be a 2kg loss in weight within 4 weeks and a 5% body weight loss within 3 months of initial use of sibutramine. if not, all Sibutramine use should be ceased.

* Sibutramine is recommended for people aged 18 - 65 years. Caution! - Sibutramine should not be used where there is a history of heart disease, heart failure,peripheral vascular disease, arrhythmias ( abnormal heart rhythms ) or stroke.

DOSAGE AND ADMINISTRATION
The recommended dose of Obestat is a 10mg capsule once daily with or without food.

DRUG INTERACTIONS
Sibutramine Hydrochloride should not be used concurrently with Monoamine Oxidase Inhibitors ( MAOI ) and serotonergic drugs ( selective serotonin reuptake inhibitors ) as a rare and serious collective of symptoms termed 'serotonin syndrome' has been reported. there should be a gap of at least 2 weeks between ceasing use of an MAOI and the start of intake of sibutramine and vice versa.

Certain drugs that may increase the heart rate/blood pressure should be used with caution when used in conjunction with sibutramine. examples of these are decongestants and cough, cold and allergy medications that contain phenylpropanolamine, ephedrine or pseudoephedrine.

SIDE EFFECTS WITH SIBUTRAMINE
MOST PEOPLE SUFFER NO SIDE EFFECTS ARISING FROM THE USE OF SIBUTRAMINE. THOSE THAT MAY OCCUR ARE AS FOLLOWS

* Dry mouth, constipation and difficulty sleeping.
* Blood pressure and pulse rate may become raised. this will need to be monitored as sibutramine use may have to cease if these increases cause possible health issues.


BODY MASS INDEX ( BMI ) EXPLAINED
BMI gives an indication of how much of the body mass consists of fat. It relates height to weight. BMI is calculated by dividing the weight value in kilograms by the square of height value in metres. for example, if the weight is 80kg and the height is 1.6 metres, the bmi is 80 divided by (1.6 x 1.6) = 31.25

BMI CLASSED AS HEALTH RISK
LESS THAN 18.5 UNDERWEIGHT SOME HEALTH RISK
18.5 TO 24.9 IDEAL NORMAL
25 TO 29.9 OVERWEIGHT MODERATE HEALTH RISK
30 TO 39.9 OBESE HIGH HEALTH RISK
40 AND OVER VERY OBESE VERY HIGH HEALTH RISK


MAINTAINING THE REDUCED WEIGHT
It will require continued effort and willpower to maintain the reduced body weight once the required weight has been attained and sibutramine use has stopped. This will be achieved by maintaining a healthy balanced diet alongside a regular exercise programme.



 
 
 

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